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Oct 21, 202212 min read

The $10 billion dollar unicorn in INmune Bio: on fast-progressors in AD, APOE4, TREM2 and EMACC

Summary APOE4, involved in different mechanisms in the brain including lipid homeostasis, is the strongest risk factor for Alzheimer’s...

Sep 23, 202212 min read

The $10 Billion unicorn in INmune Bio: the potential of XPro in Parkinson’s

Summary The evolution of the treatment failures for Parkinson’s disease has striking similarities with Alzheimer’s. Just like in...

Sep 2, 20228 min read

The FDA’s two leaps at once: on fast approval pathways and neurofilament light

Summary Neurofilament Light (NfL) is potentially the most important biomarker in neurodegenerative diseases. The FDA’s AdCom validated...

Jul 30, 20229 min read

The $10 billion unicorn in INMB: on allostatic load, and why all the others may have non-responders

Summary Allostatic load is the cumulative burden of stressors one encounters throughout life. The underlying causes/triggers for any...